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Integrated annotated Human normal Protein (IHP) Browser

Detalied information of IHP

Name

ENSP00000386611

Comment

Origin of IHP Origin Name Human genome (Ensembl) ENSP00000368066 MSIPI Not defined

Gene Origins Genename Origins CHRNA1 MSIPI Genenames in OMIM Genemap Mapping OMIM mutations to SwissProt Mapping OMIM mutations to SwissProt Mapping OMIM mutations to SwissProt Mapping OMIM mutations to SwissProt Mapping OMIM mutations to SwissProt Mapping OMIM mutations to SwissProt Mapping OMIM mutations to SwissProt Mapping OMIM mutations to SwissProt Mapping OMIM mutations to SwissProt Mapping OMIM mutations to SwissProt ACHRD Genenames in OMIM Genemap Genenames in OMIM Genemap Mapping OMIM mutations to SwissProt Mapping OMIM mutations to SwissProt Mapping OMIM mutations to SwissProt CMS2A Genenames in OMIM Genemap Genenames in OMIM Genemap Genenames in OMIM Genemap Genenames in OMIM Genemap SCCMS Genenames in OMIM Genemap Genenames in OMIM Genemap Genenames in OMIM Genemap Genenames in OMIM Genemap FCCMS Genenames in OMIM Genemap Genenames in OMIM Genemap Genenames in OMIM Genemap CHRND Genenames in OMIM Genemap Mapping OMIM mutations to SwissProt Mapping OMIM mutations to SwissProt Mapping OMIM mutations to SwissProt CHRNE Genenames in OMIM Genemap Mapping OMIM mutations to SwissProt Mapping OMIM mutations to SwissProt Mapping OMIM mutations to SwissProt Mapping OMIM mutations to SwissProt Mapping OMIM mutations to SwissProt Mapping OMIM mutations to SwissProt Mapping OMIM mutations to SwissProt Mapping OMIM mutations to SwissProt Mapping OMIM mutations to SwissProt CMS1E Genenames in OMIM Genemap CMS1D Genenames in OMIM Genemap Genenames in OMIM Genemap CHRNB1 Genenames in OMIM Genemap Mapping OMIM mutations to SwissProt Mapping OMIM mutations to SwissProt ACHRB Genenames in OMIM Genemap Mapping OMIM mutations to SwissProt Mapping OMIM mutations to SwissProt ACHA_HUMAN Mapping OMIM mutations to SwissProt Mapping OMIM mutations to SwissProt Mapping OMIM mutations to SwissProt Mapping OMIM mutations to SwissProt Mapping OMIM mutations to SwissProt Mapping OMIM mutations to SwissProt Mapping OMIM mutations to SwissProt Mapping OMIM mutations to SwissProt Mapping OMIM mutations to SwissProt Mapping OMIM mutations to SwissProt ACHRA Mapping OMIM mutations to SwissProt Mapping OMIM mutations to SwissProt Mapping OMIM mutations to SwissProt Mapping OMIM mutations to SwissProt Mapping OMIM mutations to SwissProt Mapping OMIM mutations to SwissProt Mapping OMIM mutations to SwissProt Mapping OMIM mutations to SwissProt Mapping OMIM mutations to SwissProt Mapping OMIM mutations to SwissProt ACHB_HUMAN Mapping OMIM mutations to SwissProt Mapping OMIM mutations to SwissProt ACHD_HUMAN Mapping OMIM mutations to SwissProt Mapping OMIM mutations to SwissProt Mapping OMIM mutations to SwissProt ACHE_HUMAN Mapping OMIM mutations to SwissProt Mapping OMIM mutations to SwissProt Mapping OMIM mutations to SwissProt Mapping OMIM mutations to SwissProt Mapping OMIM mutations to SwissProt Mapping OMIM mutations to SwissProt Mapping OMIM mutations to SwissProt Mapping OMIM mutations to SwissProt Mapping OMIM mutations to SwissProt ACHRE Mapping OMIM mutations to SwissProt Mapping OMIM mutations to SwissProt Mapping OMIM mutations to SwissProt Mapping OMIM mutations to SwissProt Mapping OMIM mutations to SwissProt Mapping OMIM mutations to SwissProt Mapping OMIM mutations to SwissProt Mapping OMIM mutations to SwissProt Mapping OMIM mutations to SwissProt

Interpro Annotation

IPR002394 (12.00): Nicotinic acetylcholine receptor (58~73) (92~105) (110~121) (128~146)
IPR006029 (12.00): Neurotransmitter-gated ion-channel transmembrane region (238~366)
IPR006201 (12.00): Neurotransmitter-gated ion-channel (1~103) (104~147) (148~224) (225~377)
IPR006202 (12.00): Neurotransmitter-gated ion-channel ligand-binding (22~231)
noIPR (12.00): (2~231) (232~263) (264~302) (303~377)
IPR006029 (18.00): Neurotransmitter-gated ion-channel transmembrane region (231~337) (338~377)
IPR006201 (18.00): Neurotransmitter-gated ion-channel (1~375)
IPR006202 (18.00): Neurotransmitter-gated ion-channel ligand-binding (22~236)
noIPR (18.00): (6~18) (41~302) (303~375)

4 Mutated sequence(s)

Name	Length (aa)	Type
IMS000008	13	Deletion
IMS000010	377	Point
IMS000013	377	Point
IMS015831	377	Point

Amino acid length

377 aa

Amino acid sequence viewer

	|......10|.......20|.......30|.......40|.......50|.......60|.......70|.......80|
+ 1 81 161 241 321	MEPWPLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINVDEVNQIVTTNVRLKQQW VDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNADGDFAIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQ NCSMKLGTWTYDGSVVAINPESDQPDLSNFMESGEWVIKESRGWKHSVTYSCCPDTPYLDITYHFVMQRLPLYFIVNVII PCLLFSFLTGLVFYLPTDSGEKMTLSISVLLSLTVFLLVIVELIPSTSSAVPLIGKYMLFTMVFVIASIIITVIVINTHH RSPSTHVMPNWVRKAAAEWKYVAMVMDHILLGVFMLVCIIGTLAVFAGRLIELNQQG

cDNA sequence length

1466 bp

cDNA sequence viewer

|......10|.......20|.......30|.......40|.......50|.......60|.......70|.......80|

+ 1 81 161 241 321 401 481 561 641 721 801 881 961 1041 1121 1201 1281 1361 1441

GCTCCGGTAGCCCATGGAGCCCTGGCCTCTCCTCCTGCTCTTTAGCCTTTGCTCAGGTAAGCTCGTCCTGGGCTCCGAAC ATGAGACCCGTCTGGTGGCAAAGCTATTTAAAGACTACAGCAGCGTGGTGCGGCCAGTGGAAGACCACCGCCAGGTCGTG GAGGTCACCGTGGGCCTGCAGCTGATACAGCTCATCAATGTGGTGAGAGTAAATCAGATCGTGACAACCAATGTGCGTCT GAAACAGGTAACGGTGGATTACAACCTAAAATGGAATCCAGATGACTATGGCGGTGTGAAAAAAATTCACATTCCTTCAG AAAAGATCTGGCGCCCAGACCTTGTTCTCTATAACAAGTGAGATGGTGACTTTGCTATTGTCAAGTTCACCAAAGTGCTC CTGCAGTACACTGGCCACATCACGTGGACACCTCCAGCCATCTTTAAAAGCTACTGTGAGATCATCGTCACCCACTTTCC CTTTGATGAACAGAACTGCAGCATGAAGCTGGGCACCTGGACCTACGACGGCTCTGTCGTGGCCATCAACCCGGTAGGCG ACCAGCCAGACCTGAGCAACTTCATGGAGAGCGGGGAGTGGGTGATCAAGGAGTCCCGGGGCTGGAAGCACTCCGTGACC TATTCCTGCTGCCCCGACACCCCCTACCTGGACATCACCTACCACTTCGTCATGCAGCGCCTGCCCCTCTACTTCATCGT CAACGTCATCATCCCCTGCCTGCTCTTCTCCTTCTTAACTGGCCTGGTATTCTACCTGCCCACAGACTCAGGTGGGAAGA TGACTCTGAGCATCTCTGTCTTACTGTCTTTGACTGTGTTCCTTCTGGTCATCGTGGAGCTGATCCCCTCCACGTCCAGT GCTGTGCCCTTGATTGGAAAATACATGCTGTTCACCATGGTGTTCGTCATTGCCTCCATCATCATCACTGTCATCGTCAT CAACACACACCACCGCTCACCCAGCACCCATGTCATGCCCAACTGGGTGCGGAAGGTGAGGGCAGAGTGGAAGTACGTTG CAATGGTGATGGACCACATACTCCTCGGAGTCTTCATGCTTGTTTGCATCATCGGAACCCTAGCCGTGTTTGCAGGTCGA CTCATTGAATTAAATCAGCAAGGATGAGCAGAAAATGAGCTGAGCTTAGCTCTGCCCTGGAACCTACCAGAGCAGAGAAG GGCAGGAGAGGAAGATTTGTCTACTTGCTCCACTCGCACTTATCAAACGTGTTATATTCCATACTTATTATTGATGATAA GATTTACCTTTATGTAAGTTTATGGCCTTGAAGTGTTTTCATATTGCTTCTCCCTTTAGTTCTGCTGTCTCCCTGAAGAG TGAACCCTCTTTAGTAAATGAAACTAATCACTAAAAAAAGTGTTCATTTCCAGTGTCTGGAAGAGTTTTTGCCAGGATAA CCGAGGTTTTCTGTTGCATTGTCATT

Codon usage

1

2

3

4

5

6

7

8

9

10

11

12

13

14

15

M

E

P

W

P

L

L

L

L

F

S

L

C

S

A

GCT

CCG

GTA

GCC

CAT

GGA

GCC

CTG

GCC

TCT

CCT

CCT

GCT

CTT

TAG

16

17

18

19

20

21

22

23

24

25

26

27

28

29

30

G

L

V

L

G

S

E

H

E

T

R

L

V

A

K

CCT

TTG

CTC

AGG

TAA

GCT

CGT

CCT

GGG

CTC

CGA

ACA

TGA

GAC

CCG

31

32

33

34

35

36

37

38

39

40

41

42

43

44

45

L

F

K

D

Y

S

S

V

V

R

P

V

E

D

H

TCT

GGT

GGC

AAA

GCT

ATT

TAA

AGA

CTA

CAG

CAG

CGT

GGT

GCG

GCC

46

47

48

49

50

51

52

53

54

55

56

57

58

59

60

R

Q

V

V

E

V

T

V

G

L

Q

L

I

Q

L

AGT

GGA

AGA

CCA

CCG

CCA

GGT

CGT

GGA

GGT

CAC

CGT

GGG

CCT

GCA

61

62

63

64

65

66

67

68

69

70

71

72

73

74

75

I

N

V

D

E

V

N

Q

I

V

T

T

N

V

R

GCT

GAT

ACA

GCT

CAT

CAA

TGT

GGT

GAG

AGT

AAA

TCA

GAT

CGT

GAC

76

77

78

79

80

81

82

83

84

85

86

87

88

89

90

L

K

Q

Q

W

V

D

Y

N

L

K

W

N

P

D

AAC

CAA

TGT

GCG

TCT

GAA

ACA

GGT

AAC

GGT

GGA

TTA

CAA

CCT

AAA

91

92

93

94

95

96

97

98

99

100

101

102

103

104

105

D

Y

G

G

V

K

K

I

H

I

P

S

E

K

I

ATG

GAA

TCC

AGA

TGA

CTA

TGG

CGG

TGT

GAA

AAA

AAT

TCA

CAT

TCC

106

107

108

109

110

111

112

113

114

115

116

117

118

119

120

W

R

P

D

L

V

L

Y

N

N

A

D

G

D

F

TTC

AGA

AAA

GAT

CTG

GCG

CCC

AGA

CCT

TGT

TCT

CTA

TAA

CAA

GTG

121

122

123

124

125

126

127

128

129

130

131

132

133

134

135

A

I

V

K

F

T

K

V

L

L

Q

Y

T

G

H

AGA

TGG

TGA

CTT

TGC

TAT

TGT

CAA

GTT

CAC

CAA

AGT

GCT

CCT

GCA

136

137

138

139

140

141

142

143

144

145

146

147

148

149

150

I

T

W

T

P

P

A

I

F

K

S

Y

C

E

I

GTA

CAC

TGG

CCA

CAT

CAC

GTG

GAC

ACC

TCC

AGC

CAT

CTT

TAA

AAG

151

152

153

154

155

156

157

158

159

160

161

162

163

164

165

I

V

T

H

F

P

F

D

E

Q

N

C

S

M

K

CTA

CTG

TGA

GAT

CAT

CGT

CAC

CCA

CTT

TCC

CTT

TGA

TGA

ACA

GAA

166

167

168

169

170

171

172

173

174

175

176

177

178

179

180

L

G

T

W

T

Y

D

G

S

V

V

A

I

N

P

CTG

CAG

CAT

GAA

GCT

GGG

CAC

CTG

GAC

CTA

CGA

CGG

CTC

TGT

CGT

181

182

183

184

185

186

187

188

189

190

191

192

193

194

195

E

S

D

Q

P

D

L

S

N

F

M

E

S

G

E

GGC

CAT

CAA

CCC

GGT

AGG

CGA

CCA

GCC

AGA

CCT

GAG

CAA

CTT

CAT

196

197

198

199

200

201

202

203

204

205

206

207

208

209

210

W

V

I

K

E

S

R

G

W

K

H

S

V

T

Y

GGA

GAG

CGG

GGA

GTG

GGT

GAT

CAA

GGA

GTC

CCG

GGG

CTG

GAA

GCA

211

212

213

214

215

216

217

218

219

220

221

222

223

224

225

S

C

C

P

D

T

P

Y

L

D

I

T

Y

H

F

CTC

CGT

GAC

CTA

TTC

CTG

CTG

CCC

CGA

CAC

CCC

CTA

CCT

GGA

CAT

226

227

228

229

230

231

232

233

234

235

236

237

238

239

240

V

M

Q

R

L

P

L

Y

F

I

V

N

V

I

I

CAC

CTA

CCA

CTT

CGT

CAT

GCA

GCG

CCT

GCC

CCT

CTA

CTT

CAT

CGT

241

242

243

244

245

246

247

248

249

250

251

252

253

254

255

P

C

L

L

F

S

F

L

T

G

L

V

F

Y

L

CAA

CGT

CAT

CAT

CCC

CTG

CCT

GCT

CTT

CTC

CTT

CTT

AAC

TGG

CCT

256

257

258

259

260

261

262

263

264

265

266

267

268

269

270

P

T

D

S

G

E

K

M

T

L

S

I

S

V

L

GGT

ATT

CTA

CCT

GCC

CAC

AGA

CTC

AGG

TGG

GAA

GAT

GAC

TCT

GAG

271

272

273

274

275

276

277

278

279

280

281

282

283

284

285

L

S

L

T

V

F

L

L

V

I

V

E

L

I

P

CAT

CTC

TGT

CTT

ACT

GTC

TTT

GAC

TGT

GTT

CCT

TCT

GGT

CAT

CGT

286

287

288

289

290

291

292

293

294

295

296

297

298

299

300

S

T

S

S

A

V

P

L

I

G

K

Y

M

L

F

GGA

GCT

GAT

CCC

CTC

CAC

GTC

CAG

TGC

TGT

GCC

CTT

GAT

TGG

AAA

301

302

303

304

305

306

307

308

309

310

311

312

313

314

315

T

M

V

F

V

I

A

S

I

I

I

T

V

I

V

ATA

CAT

GCT

GTT

CAC

CAT

GGT

GTT

CGT

CAT

TGC

CTC

CAT

CAT

CAT

316

317

318

319

320

321

322

323

324

325

326

327

328

329

330

I

N

T

H

H

R

S

P

S

T

H

V

M

P

N

CAC

TGT

CAT

CGT

CAT

CAA

CAC

ACA

CCA

CCG

CTC

ACC

CAG

CAC

CCA

331

332

333

334

335

336

337

338

339

340

341

342

343

344

345

W

V

R

K

A

A

A

E

W

K

Y

V

A

M

V

TGT

CAT

GCC

CAA

CTG

GGT

GCG

GAA

GGT

GAG

GGC

AGA

GTG

GAA

GTA

346

347

348

349

350

351

352

353

354

355

356

357

358

359

360

M

D

H

I

L

L

G

V

F

M

L

V

C

I

I

CGT

TGC

AAT

GGT

GAT

GGA

CCA

CAT

ACT

CCT

CGG

AGT

CTT

CAT

GCT

361

362

363

364

365

366

367

368

369

370

371

372

373

374

375

G

T

L

A

V

F

A

G

R

L

I

E

L

N

Q

TGT

TTG

CAT

CAT

CGG

AAC

CCT

AGC

CGT

GTT

TGC

AGG

TCG

ACT

CAT

376

377

Q

G

TGA

ATT

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